The AACR is
currently holding its annual meeting through Wednesday in Washington, D.C.
Levitzki, professor of biological chemistry at the Alexander Silberman
Institute of Life Sciences at the Hebrew University, will deliver his award
lecture there on Tuesday afternoon on “Eradicating Tumors by Targeting Nonviral
Vectors Carrying PolyIC.”
The AACR has
said that Levitzki was chosen for the honor in recognition of his contributions
to signal transduction therapy and his work on the development of tyrosine
kinase inhibitors as effective agents against cancer.
Levitzki’s
concept of targeted cancer therapy using protein tyrosine kinase inhibitors is
extensively used by the pharmaceutical industry worldwide to develop anticancer
drugs.
His method
of large-scale screening of synthetic compounds tested against a large spectrum
of protein kinases for specificity, followed by systematic testing in cell
lines and animal studies, became the standard procedure in most of the
laboratories working in that field.
Levitzki has
received numerous awards throughout his career, including the Israel Prize in
Biochemistry, the Wolf Prize for Medicine, the Hamilton-Fairley Award from the
European Society of Medical Oncology, the Rothschild Prize in Biology and two
Prostate Cancer Foundation Research Awards. Last year he received the Nauta
Award in Pharmacochemistry, which is the highest award from the European
Federation for Medicinal Chemistry.